A rare non-genetic disorder that causes multiple Enchondromas to grow within the bone of the affected individual.
Usually a somatic mutation (meaning the limb itself has the mutation). The genes most commonly involved are PTH1R, IDH1 or IDH2. Rare cases are transmitted from a parent.
Clinical Diagnosis can be made by x-rays.
Treatment involves straightening and lengthening limbs with internal rods or external fixators depending on the patient. In a young child a limb can often be straightened by modifying growth; hemiepiphyseodesis.
Fingers and hands tumors are often scraped and bone straightened.